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What drugs are given in chemotherapy? Drugs in this group include 5-fluorouracil, 6-mercaptopurine, cytarabine, gemcitabine, and methotrexate, among many others. Anthracycline chemotherapy attacks the enzymes inside cancer cells' DNA that help them divide and grow. They work for many types of cancer.
What is hydroxyurea used for in sickle cell? Hydroxyurea is a medicine that is used to treat certain types of cancer as well as to reduce the frequency of pain crises and the need for blood transfusions in patients with sickle cell anemia.
What does hydroxyurea do to cells? Hydroxyurea (HU) 1 is a potent inhibitor of the enzyme ribonucleotide reductase (RNR) and inhibits DNA replication in a wide variety of cells, including Saccharomyces cerevisiae (1). Budding yeast offers a simpler system in which to study the mechanism by which HU affects replication.
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